• Apocleinae
  • Amblyonychus Hermann, 1921 *
  • Eccritosia Schiner, 1866 *
  • Furcilla Martin, 1975 *
  • Mallophora Macquart, 1838 *
  • Megaphorus Bigot, 1857 *
  • Nevadasilus Artigas & Papavero, 1995 *
  • Proctacanthella Bromley, 1934 *
  • Proctacanthus Macquart, 1838 *
  • Promachella Cole & Pritchard, 1964 *
  • Promachus Loew, 1848 *
  • Efferia group
    • Albibarbefferia Artigas & Papavero, 1997 *
    • Aridefferia Artigas & Papavero, 1997 *
    • Carinefferia Artigas & Papavero, 1997 *
    • Efferia Coquillet, 1893 *
    • Nerax Hull, 1962 *
    • Pogonioefferia Artigas & Papavero, 1997 *
    • Triorla Parks, 1968 *
    • Tuberculefferia Artigas & Papavero, 1997 *
• Asilinae
  • Asilus Linnaeus, 1758 *
  • Dicropaltum Martin, 1975 *
  • Machimus Loew, 1849
  • Negasilus Curran, 1934 *
  • Neoitamus Osten Sacken, 1878 *
  • Neomochtherus Osten Sacken, 1878 *
  • Philonicus Loew, 1849 *
  • Polacantha Martin, 1975 *
  • Prolatiforceps Martin, 1975 *
  • Rhadiurgus Loew, 1849 *
  • Tolmerus Loew, 1849
  • Wyliea Martin, 1975 *
• Dasypogoninae
  • Blepharepiini
    • Blepharepium Rondani, 1848 *
  • Dasypogonini
    • Lestomyia Williston, 1884 *
    • Parataracticus Cole, 1924 *
    • Saropogon Loew, 1847 *
    • Taracticus Loew, 1872 *
  • Isopogonini
    • Comantella Curran, 1923 *
    • Cophura Osten Sacken, 1887 *
    • Hodophylax James, 1933 *
    • Nicocles Jaennicke, 1867 *
    • Omninablautus Pritchard, 1935 *
  • Lastaurini
    • Diogmites Loew, 1866
• Dioctriinae
  • Dioctriini
    • Dioctria Meigen, 1803
    • Nannodioctria Wilcox & Martin, 1942
  • Echthodopini
    • Bohartia Hull, 1958
    • Dicolonus Loew, 1866
    • Echthodopa Loew, 1866
    • Eudioctria Wilcox & Martin, 1941
    • Metadioctria Wilcox & Martin, 1941
• Laphriinae
  • Andrenosomini
    • Andrenosoma Rondani, 1856
    • Cerotainiops Curran, 1930
    • Pogonosoma Rondani, 1856
  • Atomosiini
    • Atomosia Macquart, 1838
    • Atomosiella Wilcox, 1937 *
    • Atoniomyia Hermann, 1912 *
    • Cerotainia Schiner, 1868
  • Dasylechiini
    • Dasylechia Williston, 1907 *
  • Dasytrichini
    • Orthogonis Hermann, 1914 *
  • Laphriini
    • Choerades Walker, 1851 *
    • Lampria Macquart, 1838
    • Laphria Meigen, 1803 *
• Laphystiinae
  • Laphystia Loew, 1847
  • Perasis Hermann, 1906 *
  • Psilocurus Loew, 1874
  • Zabrops Hull, 1957
• Leptogastrinae
  • Apachekolos Martin, 1957
  • Beameromyia Martin, 1957
  • Leptogaster Meigen, 1803
  • Leptopteromyia Williston, 1907
  • Psilonyx Aldrich, 1923 *
  • Tipulogaster Cockerell, 1913 *
• Ommatiinae
  • Ommatius Wiedemann, 1821
• Stenopogoninae
  • Ceraturgini
    • Ceraturgus Wiedemann, 1824
    • Myelaphus Bigot, 1882 *
  • Cyrtopogonini
    • Ablautus Loew, 1866
    • Backomyia Wilcox & Martin, 1957
    • Callinicus Loew, 1872
    • Cyrtopogon Loew, 1847
    • Eucyrtopogon Curran, 1923
    • Hadrokolos Martin, 1959
    • Heteropogon Loew, 1847
    • Holopogon Loew, 1847
    • Itolia Wilcox, 1936 *
    • Metapogon Coquillett, 1904 *
    • Nannocyrtopogon Wilcox & Martin, 1936
    • Pritchardomyia Wilcox, 1965 *
    • Sintoria Hull, 1962 *
    • Wilcoxia James, 1941 *
  • Enigmomorphini
    • Archilestris Loew, 1874 *
    • Dicranus Loew, 1851 *
    • Microstylum Macquart, 1838
    • Prolepsis Walker, 1851 *
  • Plesiommatini
    • Plesiomma Macquart, 1838 *
  • Stenopogonini
    • Ospriocerus Loew, 1866
    • Scleropogon Loew, 1866
    • Stenopogon Loew, 1847
  • Tillobromini
    • Coleomyia Wilcox & Martin, 1935
  • Willistoninini
    • Willistonina Back, 1909
• Stichopogoninae
  • Lasiopogon Loew, 1847
  • Lissoteles Bezzi, 1910 *
  • Stichopogon Loew, 1847 *
  • Townsendia Williston, 1895 (*)
• Trigonomiminae
  • Bromleyus Hardy, 1944 *
  • Haplopogon Engel, 1930
  • Holcocephala Jaennicke, 1867
  • Orrhodops Hull, 1958 *

Unplaced taxa: Dasypogon quadrinotatus Bigot, 1878; Dasypogon rubiginosus (Bigot, 1878); Eutomus lecythus (Walker, 1849)]